Abstract Urticaria is a distinctive pattern of inflammatory re sponse of the skin and/or mucous membranes charac terized by the sudden appearance of vanishing wheals, angioedema, or both, associated with pruritus. Acute forms are frequent and limited to outbreaks of less than 6 weeks; while the chronic ones have a prevalence of less than 1%, longer duration and can be spontaneous or inducible. The etiopathogenic mechanisms involved in this disease include autoallergy, autoimmunity, and inflam mation with cell activation, mainly of the mast cell, leading to its degranulation with the release of vasoac tive mediators. Along its approach, diagnostic confirmation, search for indicators of its etiopathogenesis, detection of cofactors that can modulate its activity, recognition of comorbidi ties, evaluation of possible biomarkers and the assess ment of disease activity, impact and control are essential. The pharmacological management aims to control the symptoms, until the urticaria, which is self-resolv ing, is gone. This is described in a stepwise fashion with increasing complexity.

Resumen La urticaria es un patrón distintivo de respuesta inflamatoria de piel y/o mucosas caracterizada por la aparición súbita de ronchas evanescentes, angioedema o ambos, asociados a prurito. Las formas agudas son frecuentes y se limitan a brotes de menos de 6 sema nas; mientras que las crónicas tienen una prevalencia menor al 1%, mayor duración y pueden ser espontáneas o inducibles. Los mecanismos etiopatogénicos involucrados en esta enfermedad incluyen la autoalergia, la autoinmunidad y la inflamación con la activación celular, principalmente del mastocito, lo que lleva a su degranulación con libe ración de mediadores vasoactivos. En su abordaje son fundamentales la confirmación diagnóstica; la búsqueda de indicadores de su etiopa togenia; la detección de cofactores que pueden modular su actividad; el reconocimiento de comorbilidades; la evaluación de posibles biomarcadores y, el impacto en la calidad de vida, el registro de la actividad y el control de la enfermedad. El manejo farmacológico tiene por objetivo controlar los síntomas, mientras la urticaria resuelve de forma espontánea. Este se describe de forma escalonada con una complejidad creciente.

Abstract This study evaluated the effects of biogenic structures (tree roots and crab burrows) on sediment carbon (C), sulfur (S), and iron (Fe) biogeochemistry during the wet season in the Olaria mangrove forests near the city of Cananéia, São Paulo state, Brazil and the Nobrega mangrove forest approximately 2 km from the city. Anaerobic C oxidation pathways were assessed from sediment profiles and anaerobic incubations and related to the abundance of biogenic structures in the form of pneumatophores and crab burrows. Porewater depth profiles of dissolved inorganic carbon (DIC) and SO42- were less steep in the presence than absence of biogenic structures. While Fe(II) appeared unaffected by biogenic structures, Fe(III) levels were significantly higher in the upper 4 cm of the sediment in the presence than absence of vegetation and bioturbation. Surprisingly, the concentration of Fe(III) in this layer was 2-6 times higher in the Nobrega forest (6-13 µmol cm-3) than in the Olaria forest (1.5-6.5 µmol cm-3). Accordingly, depth integrated sulfate reduction (SR) tended to be highest at Olaria, while iron reduction (FeR) was highest at Nobrega. SR accounted for 54-83% of DIC production, with no diference between forested sites, while FeR accounted for 8-24% of DIC production, with a 2-3 times higher contribution in the Nobrega versus the Olaria forest. The results suggest that mangrove roots and crab burrows in mangrove sediments only promote FeR at the expense of SR in the Nobrega forest. It appears that anthropogenic discharge from Cananéia city may have overridden the impact of biogenic structures on sediment redox conditions at Olaria, thereby diminishing the role of FeR without strong stimulation of overall C oxidation rates.

Abstract Background Cardiac magnetic resonance (CMR) has an increasing diagnostic relevance in survivors of sudden cardiac death (SCD) or unstable ventricular arrhythmia (UVA) in developed countries. Objective To evaluate retrospectively the additional role of CMR in a developing country where few resources are available, and should be used more effectively. Methods The study included SCD or UVA survivors admitted between 2009 and 2019 at a tertiary academic institution referred to CMR. Demographic, clinical, and laboratory data were collected from the medical records. CMR images and reports were reviewed and their impact on the final etiological diagnosis was determined. A descriptive analysis was performed and p<0.05 established as significant. Results Sixty-four patients, 54.9±15.4 years old, and 42 (71.9%) males. Most events (81.3%) were out of the hospital and ventricular tachycardia was the most common rhythm. Cardiovascular medications were previously used by 55 patients, and beta-blockers were the most used medications (37.5%). Electrocardiogram had electrical inactive areas in 21.9% and all of them had fibrosis at CMR. Mean left ventricular ejection fraction (LVEF) was 44±14%, with 60.9% ≤50% and only 29.7% ≤35%. Late gadolinium enhancement was identified in 71.9%, with a transmural pattern in 43.8%. Chagas cardiomyopathy was the most common etiology (28.1%), followed by ischemic cardiomyopathy (17.2%). Among 26 without a previously identified etiology, CMR could define it (15 patients – 57%). Conclusion In accordance with previous studies in developed countries, CMR was capable of increasing etiological diagnosis and identifying the arrhythmogenic substrate, allowing better care in half of the underdiagnosed patients.

Resumo Fundamento A ressonância magnética cardíaca (RMC) tem relevância diagnóstica crescente em sobreviventes de morte súbita cardíaca (MSC) ou arritmia ventricular instável (AVI) em países desenvolvidos. Objetivo Procuramos avaliar retrospectivamente o papel adicional da RMC em um país em desenvolvimento com poucos recursos disponíveis e que pode direcionar um uso mais eficaz desses recursos. Métodos Foram incluídos sobreviventes de MSC ou AVI admitidos entre 2009 e 2019 em uma instituição acadêmica terciária após a realização de RMC. Dados demográficos, clínicos e laboratoriais foram coletados dos prontuários. Imagens e laudos de RMC foram analisados e o impacto disso no diagnóstico etiológico final foi afirmado. Realizou-se análise descritiva e definiu-se p<0,05 como significativo. Resultados Sessenta e quatro pacientes, 54,9±15,4 anos, sendo 42 (71,9%) do sexo masculino. A maioria dos eventos (81,3%) foi extra-hospitalar e a taquicardia ventricular foi o ritmo mais comum. Medicamentos cardiovasculares foram utilizados anteriormente por 55 pacientes, sendo os betabloqueadores os medicamentos mais utilizados (37,5%). O eletrocardiograma apresentava áreas elétricas inativas em 21,9% e todos apresentavam fibrose na RMC. A média da fração de ejeção do ventrículo esquerdo (FEVE) foi de 44±14%, com 60,9% ≤50% e apenas 29,7% ≤35%. Identificou-se realce tardio com gadolínio em 71,9%, com padrão transmural em 43,8%. A miocardiopatia chagásica foi a etiologia mais comum (28,1%), seguida da miocardiopatia isquêmica (17,2%). Entre 26 sem etiologia previamente identificada, foi possível definir com RMC (15 pacientes - 57%). Conclusão De acordo com estudos anteriores em países desenvolvidos, a RMC foi capaz de aumentar o diagnóstico etiológico e identificar o substrato arritmogênico, permitindo melhor atendimento em metade dos pacientes subdiagnosticados.

In this work, iron ore tailing (IOT) was used for the production of two different materials: sodium silicate and geopolymers. Initially, reactions of IOT with NaOH were carried out by hydrothermal reaction in autoclave at 200 °C (1:1.5 and 1:2.5 SiO2:NaOH molar ratio) and reaction times of 4 and 8 h. X-ray fluorescence by dispersive energy (XRF), X-ray diffraction (XRD), Mössbauer spectroscopy, scanning electron microscopy (SEM-EDS) and titrations showed that IOT:NaOH ratios of 1:2.5 and reaction time 8 h completely dissolved the quartz from the IOT, obtaining a solid fraction consisting mainly of hematite and an aqueous phase of sodium silicate, which showed contents of ca. 23% SiO2 and 19% Na2O. This sodium silicate obtained was then combined with IOT (25 and 50 wt.%) to produce geopolimeric material with excellent physico-chemical properties, fast curing time and very good compressive strength results, which ranged from 41 to 58 MPa and many potential applications.

Abstract Estuaries are important features for global biogeochemical understanding, due to their highly coupled interaction between sediment and water. In those places, the land-sea transect sometimes has a gradient of physical and chemical characteristics, influencing the availability of nutrients and consequently primary production. This study aimed to observe the benthic aerobic respiration and sediment-water nutrient fluxes in a freshwater to marine transect in the Cananéia-Iguape Estuarine-Lagoon Complex (CIELC) on the southeastern Brazilian Coast. This area contains the most pristine mangrove at the limit between tropical and subtropical zones, providing an ideal observatory for ecological research programs. Intact sediment cores were incubated in laboratory to determine fluxes of O2, TCO2, and dissolved nutrients. Three different sites with different salinities were sampled during the four seasons of the year. Sediment characteristics of the sites were compared, showing higher organic matter in the lowest saline (LS) site and higher phytopigments in the highest saline (HS) site, as expected. Benthic aerobic respiration, O2 and CO2 fluxes, ranged from −0.4 to −3.2 mmol m−2h−1 and 0.1 to 1.5 mmol m−2h−1, respectively, and exhibited statistically significant variations between seasons and in a salinity gradient. Dissolved inorganic nitrogen and silicate, ranging from −228.7 to 544.8 μmol m−2h−1 and −205.8 to 4,173.5 μmol m−2h−1, respectively, were generally released from the sediment, whereas phosphate ranged from −25.2 to 29.6 μmol m−2h−1 with more variation in time and space. The LS site was characterized as a nitrogen sink and a silicate and phosphate releaser, and the HS site was characterized as a nitrogen producer and a phosphorus consumer. However, seasonal and spatial variations were observed, and the interaction between space and time factors was always highly significant, indicating that the metabolic behavior of the benthic compartment depends on both trophic and physicochemical conditions.

Resumen La isla de calor urbano superficial es una de las principales causas de la disminución del confort bioclimático en áreas donde los patrones de superficie son heterogéneos, en especial en el verano. El municipio de Oporto tiene características de uso del suelo y materiales de cubierta cuyas propiedades térmicas y radiativas son profundamente diferentes. En este sentido, el presente estudio busca examinar la influencia de la cobertura terrestre en la temperatura superficial utilizando imágenes de satélite. Las temperaturas superficiales se extrajeron de la imagen Landsat 8-OLI y se han derivado varios índices espectrales para identificar el potencial de enfriamiento por evaporación. Los principales resultados muestran que las "islas de calor urbano superficiales" se ubican mayoritariamente en el núcleo central de Oporto y las principales vías de comunicación, donde los efectos de la densificación urbana y las propiedades de recubrimiento del material utilizado impiden la evapotranspiración. Ideas destacadas: Artículo de investigación sobre la influencia de la isla de calor urbana en el municipio de Oporto, en Portugal, basado en análisis de teledetección (imagen Landsat 8-OLI).

Abstract The surface urban heat island is one of the main causes for the decrease in bioclimatic comfort in areas with heterogeneous surface patterns, especially in the summer. The municipality of Porto has characteristics of land use and roofing materials provide thermal and radiative properties that are widely disseminated. The present study seeks to influence the coverage of land cover over land surface temperature using satellite images. As land surface temperature were extracted from the Landsat 8-OLI image, several spectral indices have been derived to identify the potential for evaporative cooling. Main results show that the "superficial urban heat island" are located mainly in the central core of the city of Porto and the main communication routes, where the effects of urban densification and the material covering properties used prevent evapotranspiration, favor the increase radiation absorption and, consecutively, a significant increase in land surface temperature. Highlights: Research article on the influence of the urban heat island in the municipality of Porto, in Portugal, based on remote sensing analysis (Landsat 8 image-OLI).

Resumo A ilha de calor urbano superficial é uma das principais causas para a diminuição do conforto bioclimático em áreas onde os padrões superficiais são heterogéneos, sobretudo no verão. O município do Porto apresenta caraterísticas de uso do solo e materiais de cobertura cujas propriedades térmicas e radiativas são profundamente dissemelhantes. Neste sentido, o presente estudo procura examinar a influência da cobertura do solo sobre a temperatura de superfície, recorrendo às imagens de satélite. As temperaturas de superfície foram extraídas da imagem Landsat 8-oLI, e vários índices espectrais foram derivados para identificar o potencial de arrefecimento evaporativo. Os principais resultados mostram que as "ilhas de calor urbano superficial" se localizam maioritariamente no núcleo central da cidade do Porto e das principais vias de comunicação, onde os efeitos da densificação urbana e das propriedades materiais de cobertura utilizados impedem a evapotranspiração, favorecem o aumento da absorção radiativa e, consecutivamente, o aumento significativo de temperatura de superfície. Ideias destacadas: Artigo de investigação sobre a influência da ilha de calor urbano no município do Porto, em Portugal, a partir da análise por detecção remota (imagem Landsat 8-OLI).

Resumen La Villa Imperial de Potosí experimentó su mayor auge productivo entre 1590 y 1620. La historiografía tendió a concentrarse en el análisis de los mitayos, postulando que habrían realizado los trabajos más simples y rutinarios, siendo los trabajadores "libres" (mingas) los es pecialistas. También se propuso que, durante el período, el 30% de la mano de obra minera habría sido mitaya, y el 70% restante libre y asalariada. Dos preguntas se desprenden de estos postulados: ¿La minería de Potosí requería un porcentaje tan alto de especialistas? ¿La asociación entre trabajo libre y especialización laboral fue tan directa y generalizable? A partir de estos interrogantes iniciales se proponen algunas reflexiones sobre el mundo del trabajo minero potosino. En primer lugar, se evalúan evidencias sobre la especialización laboral, la transmisión de saberes y experiencias ligadas a las diversas tareas mineras. Por otro lado, a partir de las normas y las prácticas rastreables, se aborda la situación "polivalente" de los trabajadores mineros, que implicó la alternancia de períodos de trabajo forzado y momentos más libres. En tercer lugar, se problematizan las formas de confluencia de la división del trabajo minero y la polivalencia planteada por el sistema mitayo. Se aspira así a contribuir a la interpretación históricamente situada del complejo mundo laboral de la minería potosina.

Abstract The Villa Imperial de Potosí experienced its greatest productive boom from 1590 to1620. The historiography tended to concentrate on the analysis of the mitayos, postulating that they would have carried out the less specialized and routine work, with the "free" work ers (mingas) being the specialists. It was also proposed that, during the period, 30% of the mining labor force would have been mitaya, and the remaining 70% free and salaried. Two questions arise from these postulates: Did mining in Potosí require such a high percent age of specialists, and was the association between free labor and labor specialization so direct and generalizable? Based on these initial questions, some considerations about the world of mining labor in Potosí are proposed. Firstly, we evaluate evidence on labor specialization, the transmission of knowledge, and experiences linked to the different mining tasks. Secondly, based on traceable norms and practices, the "polyvalent" situation of the mine workers, which implied the alternation of periods of forced labor and spare time, is addressed. Thirdly, the forms of convergence of the division of mining labor and the polyvalence posed by the mitayo system are problematized. The aim is to contribute to the historically situated interpretation of the complex labor world of mining in Potosí.

Resumen: El objetivo de este estudio fue conocer las prácticas y la percepción sobre los riesgos de los plagui cidas domésticos (PDs) en madres y padres de niños en etapas tempranas del desarrollo. Sujetos y Método: Investigación de diseño cualitativo mediante entrevistas a madres y padres en 18 domicilios con niños de 0 a 3 años afiliados al Seguro de Salud del Hospital Italiano de Buenos Aires en el año 2015. Se identificaron categorías analíticas, se conceptualizaron categorías analíticas interpretativas de mayor nivel de abstracción y finalmente se construyeron diagramas para representar y organizar los hallazgos. Resultados: Las entrevistas mostraron que las madres y padres: 1) Utilizaban habi tualmente PDs, 2) Mostraron en general baja preocupación por los peligros para la salud de los PDs y productos químicos hogareños excepto un grupo pequeño más sensibilizado, 3) Les preocupaba más las picaduras de insectos en sus hijos que la exposición a PDs, 4) Confiaban en los servicios de fumigación y/o en el marco normativo que los regula, y 5) Manifestaron interés en que el pediatra les brindara información acerca de los productos químicos que se utilizan diariamente en el hogar. Otras categorías analíticas mostraron un ajuste constante entre toxicidad, patogenicidad, higiene y bienestar. Conclusiones: Dado que los niveles de exposición hogareña considerados inocuos para adultos pueden ser toxicológicamente relevantes para individuos en desarrollo, los entes de gobierno y salud deberían proveer a los padres de herramientas intelectuales para decodificar los mensajes del mercadeo de PDs, así como para conceptualizar la relación entre contacto con PDs y trastornos de salud infantil.

Abstract: The objective of this work was to know the practices and risk perception of household pesticides (HPs) of mothers and fathers of children in early developmental stages. Subjects and Method: Qualitative research carried out in 2015. We conducted interviews in 18 homes with mothers and fathers of children aged 0 to 3 years registered in the General Health Insurance Plan of the Hospital Italiano de Buenos Aires (Metropolitan Area of Buenos Aires). The analytical categories were identified, interpretive analytical categories of higher-level abstraction were conceptualized, and finally, diagrams were constructed to represent and organize the findings. Results: The interviews showed that mothers and fathers: 1) used HPs regularly, 2) showed low concern for the health hazards of HPs and other household chemicals, except for a small, more sensitized group of parents, 3) they were more concerned regarding mosquito bites than exposure of their children to HPs, 4) relied on fumigation services and the normative framework that regulates them, and 5) expressed interest and willingness to receive more information and orientation from the pediatrician about the safe use of chemical products at home. Other analytical categories showed a constant parental adjustment between toxicity, pathogenicity, hygiene, and well-being. Conclusions: Since home exposures levels to HPs considered safe for adults may be toxicologically relevant for young children, government and health agencies should provide parents with tools to decode HPs marketing and publicity messages, as well as to conceptualize the relationship between HPs use and childhood health disorders.

Abstract Background: The ECHO® (Extension for Community Healthcare Outcomes) project is a model of distance medical education developed in the United States to support health professionals in the management of patients with complex diseases. Since 2019, it has been implemented in atopic dermatitis (AD) in Argentina. The program consists of the periodic presentation of clinical cases by videoconference, virtual classes, and a permanently available open chat between professionals in charge of patients with AD and a group of experts. Objective: The objective of this study was to analyze the impact of the ECHO Project AD on the medical knowledge and medical skills of Argentinian health professionals when treating patients with AD. Methods: A survey was carried out among the participants in order to evaluate the impact of the program on the care of patients with AD. Results: ECHO Project AD revealed a significant improvement in the management of patients with AD. The program contributed to the interpretation and use of severity scores, use of phototherapy, and management and prescription of both classic and innovative topical and systemic treatments. Study limitations: The reduced number of participants and the short period of time. The answers of the survey may be biased by the enthusiasm of the participants. Conclusions: The ECHO project is an educational tool that enhances the medical skills of doctors and institutions, in which a climate of a partnership comes first and the participants look forward to learning from experiences, successes, and mistakes from one another, producing a scientific hub in constant evolution.

Abstract This study presents the implementation of a portable module designed for autonomous analysis of sea-surface inorganic nutrients onboard vessels of opportunity, as an additional tool for assessing the levels of eutrophication risk. The study was carried out during August-mid-September 2019 in the Ria de Arousa and outer shelf area (NW-Iberian coastal upwelling system). During this period, the distributions of the measured sea-surface concentrations of nitrate and phosphate were compared according to three Oceanographic Environments (OEs). The OEs were defined according to the interplay between upwelling/downwelling events and river discharge on the coastal system. The nutrient measurements agreed well with the OEs, showing that the portable module is a useful tool for opportune measurements of sea-surface nutrients and can serve as a complement for the available monitoring networks. An initial evaluation of the eutrophication risk in this area indicated low risk levels (following the Environmental European Agency criteria) for most of the measured points in summer, except for some vulnerable areas under certain OEs. Nutrient concentrations are sensitive to periods of Sustained Upwelling events, reaching medium risk levels (7.14 - 9.05 µmol L-1 for nitrate and 0.39 - 0.64 µmol L-1 for phosphate) in inner parts of the Ria de Arousa. These areas are characterized by abrupt bathymetric changes that channel and intensify the upwelling processes, increasing sea-surface nutrient concentrations. High eutrophication risk levels of phosphate (1.53 µmol L-1) were detected close to the coastline during Upwelling Relaxation periods. Under these conditions, continental flows, previously retained by the upwelling, are able to expand. The location of these samples and the difference in concentration between phosphate and nitrate indicate a most likely source in wastewater outflows. Our results highlight the need for deeper studies on the synergy between upwelling/downwelling processes and the continental water discharges and its modulation of sea-surface nutrients.

In this work, we describe a sustainable alternative to recover iron from two iron ore tailings (IOT) using hydrogen reduction at relatively low temperatures followed by magnetic separation. X-ray powder diffraction (XRD), inductively coupled plasma (ICP), atomic absorption (AA), Mössbauer, scanning electron microscopy (SEM/EDS), Raman and thermogravimetry (TG) analyses indicated that the Fe oxide present in the IOTs (sandy tailing (ST) and mud tailings (MT)), can be reduced with H2 at 500 ºC to produce α-Fe. Upon magnetic separation the mud tailing produced a 77 wt.% magnetic fraction increasing the Fe content from 19.2 to ca. 56 wt.% of Fe. On the other hand, the sandy tailing resulted in a 15 wt.% magnetic fraction increasing the Fe content from 19.2 to 70 wt.%. These results indicate that up to 86% of iron can be recovered from the IOT wastes already in the metallic form which can be very interesting for the steel industry.

Considering the bicentenary of Brazil’s Independence in 2022 and that this year was proclaimed by UNESCO as the International Year of Basic Sciences for Sustainable Development, in mid-2021 the Brazilian Chemical Society (SBQ) launched the “Post 2022 Chemistry Movement - Sustainability and Sovereignty”, with the main goal of promoting different activities so that chemistry contributes for the sustainable development and sovereignty of Brazil in the coming years. One of these activities is the proposal of an action plan, with goals to be achieved by 2030 and 2050. This article describes in detail how this action plan was formulated by a working group, with the help of an advisory council and interviews of 18 professionals from universities, the government, industries, the third sector and other organizations. Mimicking the Agenda 2030 SDGs, the resulting action plan is based on two broad Chemistry Sustainable Development Goals: promoting sustainability through chemistry in basic education, and promoting sustainability in the industry and university through science, technology, innovation, and education (STI&E) in chemistry. After the definition of three driving technological challenges in STI&E, they shall be successively implemented through different actions starting in 2023 yet.

RESUMEN Los testigos del ciberacoso juegan un importante papel en la resolución de dichas situaciones, lo que es útil para proponer estrategias de autorregulación que les permitan implicarse en comportamientos prosociales en estos contextos. Proponemos que las intervenciones que se sirven de juegos serios con agentes sociales basados en perfiles pueden potenciar el comportamiento prosocial de los testigos de ciberacoso. Se llevó a cabo un estudio piloto cuasiexperimental de medidas repetidas pre/post. Se asignó a 194 alumnos de 7º y 8º a tres condiciones, condición experimental (n = 103, Medad = 13.91, SD = 1.02, 53.3% varones), condición alternativa (n = 37, Medad = 14, SD = 0.86, 54.1% mujeres) y condición control (n = 54, Medad = 13.92, SD = 0.85, 50.9% mujeres). En el análisis de covarianza los jugadores tenían un mayor nivel de comportamiento prosocial asertivo en comparación con otros participantes. En un modelado multinivel de datos longitudinales de archivo quienes no tenían experiencia en el juego tendían a interpretar más las situaciones de ciberacoso como no serias, a evitar asumir la responsabilidad de intervenir y a participar en comportamiento agresivo hacia la víctima. Los jugadores tendían a dar más apoyo y eran menos agresivos con las víctimas de su grupo que con las de otro grupo. Se presentan ideas sobre el desarrollo de juegos que potencien el comportamiento prosocial en testigos de ciberacoso.

ABSTRACT Bystanders of cyberbullying play an important role in the resolution of such situations and therefore, it is beneficial to promote self-regulation strategies that enable them to engage in prosocial behavior in these contexts. We propose that serious game-based psychosocial interventions with profile-based social agents can encourage prosocial bystander behavior in cyberbullying. A pilot quasi-experimental study with repeated and pre/post measurements was performed. We randomly assigned 194 7th and 8th graders to three conditions, namely experimental condition (n = 103, Mage = 13.91, SD = 1.02, 53.3% male); alternative condition (n = 37, Mage = 14, SD = 0.86, 54.1% female) and control condition (n = 54, Mage = 13.92, SD = 0.85, 50.9% female). An analysis of covariance showed that players revealed higher levels of prosocial assertive behavior when compared to other participants. Through multilevel modelling of longitudinal log-file data, we found that those who did not experience the game tended to interpret the cyberbullying situations more as non-serious, avoid assuming responsibility for intervening, and engage in aggressive behavior toward the victim. Players tended to support more and were less aggressive with victims from their in-group than those from the out-group. Insights for the development of games to promote prosocial behavior in bystanders of cyberbullying are presented.

Currently, approximately 1.4 billion tons per year of iron ore tailing wastes (IOT) are generated, mainly in Australia, Brazil, and China. This work describes the characterization and application of two typical IOT, i.e., fine and coarse wastes. The physicochemical characterization of these IOT by different techniques such as XRF (X-ray fluorescence), XRD (X-ray diffraction), Mössbauer spectroscopy, and granulometry, indicates for the fine tailing a composition of Fe2O3/FeOOH (10-55%), SiO2 (18-65%) and Al2O3 (up to 15%) with particles of 6-40 µm, whereas the coarse tailing presents 40-150 µm particles with the composition of 8-48% Fe2O3/FeOOH, 30-90% SiO2 and Al2O3 (up to 20%). The main IOT applications discussed in this review are related to civil construction (aggregates for concrete, mortar, Portland cement additives), ceramic industry, geopolymer, synthesis of new materials such as zeolites, mesoporous silica, carbon nanotubes, adsorbents, catalysts for different reactions, in batteries and in fuel cells. It was also carried out an analysis of patents related to IOT applications and the main technological and market barriers that hinder the industrial and commercial uses of these wastes.